3 papers2 findings
p-Tau217
no changein humans1upin humans1
Tuberous sclerosis complex has no effect on p-Tau217 in humans (β = 0.17, SE = 0.09, p < 0.071).
Humanscompared to AD
Plasma tau-217 levels rise early in tuberous sclerosis complex
medRxiv : the preprint server for health sciences11 Sep 2026Preprint
Tuberous sclerosis complex increases p-Tau217 in humans (β = -0.21, SE = 0.05, p < 0.0001).
Humansin TSC patients relative to cognitively unimpaired controls
Plasma tau-217 levels rise early in tuberous sclerosis complex
medRxiv : the preprint server for health sciences11 Sep 2026Preprint
Novartis Pharmaceuticals Corporation
Company2 trialsPhase 3324 people
2 trialsPhase 3260 people
1 trialPhase 2/360 people
Peking Union Medical College Hospital
1 trialPhase 298 people
1 trialPhase 264 people
1 trialPhase 252 people
1 trialPhase 230 people
1 trialPhase 215 people
Log2 ptau-217 concentrations were significantly higher in 63 people with tuberous sclerosis complex than in 116 cognitively unimpaired controls (p < 0.0001).Log2 ptau-217 concentrations were significantly higher in 63 people with tuberous sclerosis complex than in 116 cognitively unimpaired controls (p < 0.0001).