PARP1 expression
3 papers1 finding
- Humans1
- Animals2
Interventions
1Nicotinamide
no changein rats1
1 study
Nicotinamide
no changein rats1
Nicotinamide has no effect on PARP1 expression in rats.
“NAm markedly attenuated PARP-1 cleavage induced by diabetes, but did not affect the parp-1 gene expression.”
Animalsstreptozotocin-induced diabeteslivertwo weeksmales
Nicotinamide prevention in diabetes-induced alterations in the rat liver
Endocrine regulations1 Jan 2023
Latest
2 in 12 monthsFrontiers in Immunology
Aerobic exercise combined with FK866 ameliorates Alzheimer's disease-like pathology in APP/PS1 mice with NAMPT abnormality
Experiments in miceExercise
Psychoneuroendocrinology
The association between telomere length and expression of DNA repair genes as a biological trace of cumulative lifetime stress
Cohort study of 65 peoplePopulations
Ecotoxicology and Environmental Safety
PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence
Cohort study in peopleTelomerase and telomere maintenance
bioRxiv
Tissue-Specific Activation of Microhomology-Mediated End Joining with Age Reflects Dynamic Rewiring of DNA Repair in Rats
Preprint: experiments in animalsDNA repair
GeroScience
The PARP inhibitor olaparib promotes senescence in murine macrophages
Experiments in mouse cellsCellular senescence
Journal of Translational Medicine
Nicotinamide mononucleotide combined with PJ-34 protects microglial cells from lipopolysaccharide-induced mitochondrial impairment through NMNAT3-PARP1 axis
Experiments in cellsInterventions
Experimental Gerontology
Obesity exacerbates postoperative cognitive dysfunction by activating the PARP1/NAD⁺/SIRT1 axis through oxidative stress
Experiments in animalsMechanisms
Advanced Biology
NAMPT/NAD⁺/PARP1 Pathway Regulates CFA-Induced Inflammatory Pain via NF-κB Signaling in Rodents
Experiments in animalsMechanisms
Acta Pharmacologica Sinica
Macrod1 suppresses diabetic cardiomyopathy via regulating PARP1-NAD⁺-SIRT3 pathway
Experiments in animalsMechanisms
Aging Cell
MiR-203 improves cardiac dysfunction by targeting PARP1-NAD⁺ axis in aging murine
Experiments in animalsInterventions