P38 MAPK
Biomarker1 paper
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10bioRxivCellsPreprint
DNA polymerase kappa supports genome repair in cultured neurons
In mouse and human neurons, depleting POLK reduced repair-associated DNA synthesis and induced senescence-like stress, while augmenting POLK lowered…In mouse and human neurons, depleting POLK reduced repair-associated DNA synthesis and induced senescence-like stress, while augmenting POLK lowered DNA damage markers.
Frontiers in BioscienceCells
Mechanism of the NAMPT-SIRT2-Lactate Axis in Senescence of Human Nucleus Pulposus Cells
Research SquareModel organismsPreprint
HSP-1/HSPA8 directs selective translation towards longevity or immunity
Biochemical and Biophysical Research CommunicationsAnimals
Mitochondria-targeted esculetin mitigates age-associated cardiac remodeling through coordinated activation of AMPK-SIRT1 and inhibition of p38 MAPK signaling
European Journal of PharmacologyModel organisms
Cycloastragenol extends lifespan and enhances stress resistance in Caenorhabditis elegans by inhibiting IIS pathway and activating p38 MAPK-mediated innate immunity
Scientific ReportsAnimals
Targeting TWEAK to enhance mitochondrial biogenesis and attenuate age-related muscle mass loss
AHA Scientific Sessions 2025 AbstractAnimals