Ovarian primordial follicle reserve
1 paper2 findings
- Animals1
Interventions
1Caloric restriction
no changein mice1downin mice1
1 study
Caloric restriction
no changein mice1downin mice1
Caloric restriction has no effect on ovarian primordial follicle reserve in mice.
“Short-term CR, whether initiated early or late, did not preserve the ovarian reserve.”
Animalsshort-term CR (3-7 months or 7-11 months)30% caloric restrictionovaryfemales
Timing and duration of calorie restriction determine its impact on ovarian aging in female mice
npj aging9 Oct 2025
Caloric restriction protects against ovarian primordial follicle reserve in mice.
“Long-term CR reduced body mass, improved insulin sensitivity, preserved the ovarian primordial follicle reserve, and attenuated ovarian macrophage infiltration compared to AL-fed mice.”
Animals30% caloric restrictionovary3-11 monthsfemales
Timing and duration of calorie restriction determine its impact on ovarian aging in female mice
npj aging9 Oct 2025