Oral Microbiome Aging Acceleration Score

Biomarker

1 paper5 findings

  • Humans1

Effects

2

Heart attack risk prediction

upin humans1

1 study
  1. Oral Microbiome Aging Acceleration Score improves heart attack risk prediction in humans (AUC 0.79 vs. 0.76).

    “heart attack (AUC 0.79 vs. 0.76, P = 0.016) beyond conventional risk factors.”

    Humansbeyond conventional risk factors

    Oral microbiome signatures predict biological age and host health

    Nature communications17 Apr 2026

Cancer risk prediction

upin humans1

1 study
  1. Oral Microbiome Aging Acceleration Score improves cancer risk prediction in humans (AUC 0.70 vs. 0.67).

    “enhanced risk prediction for cancer (AUC 0.70 vs. 0.67, P = 0.009)”

    Humansbeyond conventional risk factors

    Oral microbiome signatures predict biological age and host health

    Nature communications17 Apr 2026

Associations

3

Estimated glomerular filtration rate

downin humans1

1 study
  1. Oral Microbiome Aging Acceleration Score is associated with estimated glomerular filtration rate in humans (β = -0.066).

    “correlated with impaired kidney function (lower eGFR: β = -0.066, P = 5.22×10−4)”

    Humanskidney

    Oral microbiome signatures predict biological age and host health

    Nature communications17 Apr 2026

More on Estimated glomerular filtration rate

Frailty

upin humans1OR 1.05

1 study
  1. Oral Microbiome Aging Acceleration Score predicts frailty in humans (OR = 1.05).

    “The OMAA Score independently predicted all-cause mortality (HR = 1.05, P = 0.024) and frailty (OR = 1.05, P = 0.008)”

    Humans

    Oral microbiome signatures predict biological age and host health

    Nature communications17 Apr 2026

Mortality

upin humans1HR 1.05

1 study
  1. Oral Microbiome Aging Acceleration Score predicts mortality in humans (HR = 1.05).

    “The OMAA Score independently predicted all-cause mortality (HR = 1.05, P = 0.024)”

    Humans

    Oral microbiome signatures predict biological age and host health

    Nature communications17 Apr 2026

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