Observed amplicon sequence variants richness

1. Observed amplicon sequence variants richness is associated with cardiovascular-kidney-metabolic syndrome in humans (OR 0.98, 95% CI 0.97-1.00).

   “each unit increase in observed amplicon sequence variants was associated with a 2% lower odds of advanced CKM (odds ratio = 0.98, 95% confidence interval = 0.97-1.00)”

   Humansadvanced CKM (stages 3-4)mouthn = 4,834

   Association between oral microbiome diversity and cardiovascular-kidney-metabolic syndrome in US adults: Analysis of NHANES 2009 to 2012

   Medicine·3 Jul 2026

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