Number of differential alternative splicing genes

1. Caloric restriction increases number of differential alternative splicing genes in mice.

   “The total number of DAS genes also increased with increasing CR levels and was largely tissue-specific.”

   AnimalsC57BL/6 miceepididymal white adipose tissue, liver, hypothalamus, gastrocnemius muscle, testes, and stomach0–40% calorie restriction at 10% increments3 monthsmales

   A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction

   Life metabolism·11 Feb 2026

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