Nrf2 protein expression

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Frontiers in PharmacologyOct 8

Formononetin improved healthspan via the P53/P21/CDK4 pathway in SAMP8 mice and DAF-16/SKN-1 signaling pathway in C.elegans

Experiments in miceInterventions

AntioxidantsJun 26

Loss of NRF2 During Aging Contributes to Myocardial Functional Decline

Experiments in monkeysNRF2–KEAP1 antioxidant response

Journal of Advanced ResearchOct 13

MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis

Experiments in miceOsteoarthritis

Biochemical and Biophysical Research CommunicationsMar 27

Long-term aerobic exercise enhances liver health: miRNA regulation and oxidative stress alleviation

Experiments in ratsAerobic exercise

Experimental GerontologyMay 28

Muscle-specific PGC-1α modulates mitochondrial oxidative stress in aged sarcopenia through regulating Nrf2

Experiments in miceNRF2–KEAP1 antioxidant response

Sleep & BreathingJul 16

Intermittent hypoxia induces hepatic senescence through promoting oxidative stress in a mouse model

Experiments in animalsMechanisms

BiogerontologyJun 8

Long-term detraining reverses the improvement of lifelong exercise on skeletal muscle ferroptosis and inflammation in aging rats: fiber-type dependence of the Keap1/Nrf2 pathway

Experiments in animalsInterventions

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za ZhiAug 20

Study on the Protective effect and mechanism of Nicotinamide Riboside on lung injury in paraquat intoxicated mice

Experiments in animalsInterventions