Experimental & Molecular Medicine
Kidney disease platelets can halt division in immune cells in the lab
Cell experiments implicated tiny particles released by these platelets and an RNA molecule they carried in this premature non-dividing state.Cell experiments implicated tiny particles released by these platelets and an RNA molecule they carried in this premature non-dividing state.
Experiments in healthy-donor CD8+ T cells, 7 days, against T cells with healthy-donor plateletsKidney
Limit: Senescence markers increased, but platelet-derived microparticles did not significantly affect T-cell proliferation