Biochimica et Biophysica Acta Molecular Basis of Disease
Low cell-attachment protein levels linked to heart aging in mice
Mice with one working copy of the protein’s gene had enlarged, scarred hearts and poorer pumping, resembling changes in aged mice.Mice with one working copy of the protein’s gene had enlarged, scarred hearts and poorer pumping, resembling changes in aged mice.
Experiments in aged and Cdon+/- miceMechanisms
Limit: Whether changing CDON affects heart aging in people remains untested