Microglial states
1 paper
- Animals1
Funding
1 grant since 2024Agence Nationale de la Recherche€696.1k
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28 in 12 monthsResearch Square
MA-5 attenuates disease-associated transcriptomic aging and pathological microglial states in Gaucher disease
Preprint: experiments in miceInterventions
Cell Reports
Core activation program and selective regional responsiveness of microglia during aging and parabiosis
Experiments in miceImmune response
Nature Communications
Youth-associated protein TIMP2 regulates microglial state and function in healthy and aged mice
Experiments in miceMechanisms
medRxiv
TMEM106B haplotypes show distinct associations with tau and TDP-43 pathologies in the aging brain
Preprint: cohort study of 1,299 peopleMechanisms
Nature Genetics
Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease
Cohort study of 1,607 peopleMechanisms
Experimental Gerontology
In silico analysis of transcriptomic datasets reveals nonlinear gene expression trajectories in aging microglia and Alzheimer's disease
Computational studyMechanisms
Nature Aging
Spatial mapping and senolytic targeting of senescent and disease-associated microglia in aged mouse brain white matter
Experiments in animalsInterventions