Annals of Neurology
Associations of Heavy Metals with Cognitive Function: An Epigenome-Wide View of DNA Methylation and Mediation Analysis
Cohort study of 155 peopleDNA methylation
Papers on methylation levels
444 papers12 new in 30 days
Thursday, April 25
Wednesday, April 24
Bioinformatics
MammalMethylClock R package: software for DNA methylation-based epigenetic clocks in mammals
Computational studyAI & data
Saturday, April 20
Journal of Cachexia, Sarcopenia and Muscle
DNA methylation of skeletal muscle function-related secretary factors identifies FGF2 as a potential biomarker for sarcopenia
Case-control study in peopleSarcopenia
Friday, April 12
Thursday, April 4
Regenerative Therapy
Mesenchymal stem cells reverse thymus aging by reprogramming the DNA methylation of thymic epithelial cells
Experiments in monkeysMesenchymal stem cells
Tuesday, April 2
Molecular Ecology
Epigenetic age estimation of wild mice using faecal samples
Experiments in miceBiomarkers
Saturday, March 30
Molecular Ecology Resources
Epigenetic clocks, sex markers and age-class diagnostics in three harvested large mammals
Experiments in animalsEpigenetic clock
bioRxiv
Global DNA Hypomethylation as a Biomarker of Accelerated Epigenetic Ageing in Primates
Preprint: experiments in animalsBiomarkers
Tuesday, March 19
The European Journal of Neuroscience
Homocysteine-potentiated Kelch-like ECH-associated protein 1 promotes senescence of neuroblastoma 2a cells via inhibiting ubiquitination of β-catenin
Experiments in mouse cellsCellular senescence
Thursday, March 14
Archives of Toxicology
Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration
Case-control study of 1,342 peopleDNA methylation
Tuesday, March 5
Experimental Gerontology
Sarcopenia is associated with hypomethylation of TWEAK and increased plasma levels of TWEAK and its downstream inflammatory factor TNF-α in older adults: A case-control study
Case-control study of 152 peopleTNF signaling
Wednesday, February 28
Aging Cell
Epigenome-wide analysis of frailty: Results from two European twin cohorts
Study of 829 peopleBiomarkers
Wednesday, February 21
GeroScience
Epigenetic clock in the aorta and age-related endothelial dysfunction in mice
Experiments in miceEndothelial dysfunction
Monday, February 19
Cellular and Molecular Biology
An age classification model based on DNA methylation biomarkers of aging in human peripheral blood using random forest and artificial neural network
Computational studyBiomarkers
Tuesday, February 13
Clinical Epigenetics
Kidney-specific methylation patterns correlate with kidney function and are lost upon kidney disease progression
Cohort study in peopleDNA methylation
Wednesday, February 7
Journal of Racial and Ethnic Health Disparities
Perceived Experiences of racism in Relation to Genome-Wide DNA Methylation and Epigenetic Aging in the Black Women's Health Study
Cohort study of 384 peoplePopulations
Monday, February 5
Thursday, February 1
Thursday, January 18
Experimental Gerontology
14-Week exercise training modifies the DNA methylation levels at gene sites in non-Alzheimer's disease women aged 50 to 70 years
Non-randomized trial in 40 peopleCombined aerobic and resistance training
Monday, January 15
Biomedical Reports
CpG methylation changes in Alu repetitive sequences in normal aging due to diastolic hypertension in human dermal fibroblasts from the facial area
Cross-sectional study in peopleDNA methylation
Friday, December 22
Thursday, December 21
Journal of Theoretical Biology
Exponential dynamics of DNA methylation with age
Study in peopleDNA methylation
bioRxiv
A comprehensive map of the ageing blood methylome
Preprint: cohort study of 32,000 peopleMechanisms
Thursday, December 14
Translational Psychiatry
Identification of candidate DNA methylation biomarkers related to Alzheimer's disease risk by integrating genome and blood methylome data
Study in peopleBiomarkers
bioRxiv
Imputation approaches and quality standards for single-cell epigenetic age predictions
Preprint: computational studyBiomarkers
Saturday, December 9
Wednesday, December 6
Experimental Brain Research
Effects of exercise-targeted hippocampal PDE-4 methylation on synaptic plasticity and spatial learning/memory impairments in D-galactose-induced aging rats
Experiments in 45 ratsExercise
Friday, December 1
Epigenetics Communications
Connections between cross-tissue and intra-tissue biomarkers of aging biology in older adults
Cohort study of 2,406 peopleBiomarkers
Saturday, November 25
Fa Yi Xue Za Zhi
Cross-Platform Application of DNA Methylation Age Estimation Model in Eastern Chinese Han Population
Cross-sectional study of 48 peopleBiomarkers
Monday, November 13
Evolution, Medicine, and Public Health
Epigenetic aging differences between Wichí and Criollos from Argentina: Insights from genomic history and ecology
Cross-sectional study in peoplePopulations