Metabolism, insulin signalling, and immune regulation gene signatures

Normative-ageing subtype is associated with metabolism, insulin signalling, and immune regulation gene signatures in humans.

“was enriched for genes involved in metabolism, insulin signalling, and immune regulation.”

Humanscerebral cortexn = 952

Network subtypes of cortical similarity reveal molecular correlates of normative and compensatory ageing associated with longevity-gene expression

medRxiv·20 Oct 2025Preprint