Membrane lipid composition

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Alpha-synuclein pathology alters lipids in mice and human cells

In mouse midbrain and cultured human neurons, alpha-synuclein pathology led to shorter, more saturated lipid chains, an effect largely reversed in mice by intermittent…In mouse midbrain and cultured human neurons, alpha-synuclein pathology led to shorter, more saturated lipid chains, an effect largely reversed in mice by intermittent fasting.

Preprint: experiments in miceMechanisms