M1 microglia activation

1. EPIGALLOCATECHIN-3-GALLATE decreases M1 microglia activation in rats (30.03 ± 7.73% vs. 51.00 ± 9.83% (p < 0.001)).

   “M1 phenotype activation was significantly lower (30.03 ± 7.73% vs. 51.00 ± 9.83%, p < 0.001)”

   Animalsfollowing general anesthesia with isoflurane7 daysmales

   Preventive Effect of Epigallocatechin-3-Gallate on Postoperative Cognitive Dysfunction in Aged Rats via Modulation of Microglial Differentiation: An Experimental Animal Study

   International journal of molecular sciences·23 Nov 2025

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