M2 microglia activation

1. EPIGALLOCATECHIN-3-GALLATE increases M2 microglia activation in rats (17.61 ± 5.52% vs. 5.99 ± 2.46% (p < 0.001)).

   “M2 phenotype activation was significantly higher (17.61 ± 5.52% vs. 5.99 ± 2.46%, p < 0.001) in the EGCG group than in the control group.”

   Animalsfollowing general anesthesia with isoflurane7 daysmales

   Preventive Effect of Epigallocatechin-3-Gallate on Postoperative Cognitive Dysfunction in Aged Rats via Modulation of Microglial Differentiation: An Experimental Animal Study

   International journal of molecular sciences·23 Nov 2025

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