Lysosomal enzyme activities
2 papers2 findings
- Cells2
Upstream
1Donor age
no changein human cells1
1 study
Donor age
no changein human cells1
Donor age has no effect on lysosomal enzyme activities in human cells.
“These impairments culminate into incomplete elimination of damaged mitochondria, despite preserved activity of the lysosomal enzymes assessed.”
Cellsenzymes assessed in the context of age-related mitochondrial and mitophagy impairmentsinduced neuron
Decline in mitochondrial health and lysosomal acidification in human neurons during normal aging
bioRxiv (Cold Spring Harbor Laboratory)13 Apr 2026Preprint
Associations
1Age
mixedin rats1
1 study
Age
mixedin rats1
Age is associated with lysosomal enzyme activities in rats.
“opposite patterns of change were often observed in the activities in parenchymal cells and in nonparenchymal cells.”
AnimalsBN/BiRij rats; comparison of liver cell populationsliver parenchymal and nonparenchymal cellsfemales
Mechanisms of ageing and development1 Jan 1976
Funding
1 grant since 2017Fonds Wetenschappelijk Onderzoek
Latest
1 in 12 monthsbioRxiv
Decline in mitochondrial health and lysosomal acidification in human neurons during normal aging
Preprint: experiments in human cellsLysosome
Mechanisms of Ageing and Development
Lysosomal enzyme activities in parenchymal and nonparenchymal liver cells isolated from young, adult and old rats
Experiments in rat cellsLysosome