Lysosomal enzyme activities

Biomarker

2 papers2 findings

  • Cells2

Upstream

1

Donor age

no changein human cells1

1 study
  1. Donor age has no effect on lysosomal enzyme activities in human cells.

    “These impairments culminate into incomplete elimination of damaged mitochondria, despite preserved activity of the lysosomal enzymes assessed.”

    Cellsenzymes assessed in the context of age-related mitochondrial and mitophagy impairmentsinduced neuron

    Decline in mitochondrial health and lysosomal acidification in human neurons during normal aging

    bioRxiv (Cold Spring Harbor Laboratory)13 Apr 2026Preprint

Associations

1

Age

mixedin rats1

1 study
  1. Age is associated with lysosomal enzyme activities in rats.

    “opposite patterns of change were often observed in the activities in parenchymal cells and in nonparenchymal cells.”

    AnimalsBN/BiRij rats; comparison of liver cell populationsliver parenchymal and nonparenchymal cellsfemales

    Lysosomal enzyme activities in parenchymal and nonparenchymal liver cells isolated from young, adult and old rats

    Mechanisms of ageing and development1 Jan 1976

Funding

1 grant since 2017

Fonds Wetenschappelijk Onderzoek

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 1May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 in 12 months