Lysosomal ceroid

1 paper2 findings

Animals1

Interventions

1

Ntbuha

downin human cells1downin mice1

1 study

Ntbuha decreases lysosomal ceroid in mice.
“In Ppt1(-/-) mice, which mimic INCL, NtBuHA crossed the blood-brain barrier, depleted lysosomal ceroid”
Animalsin Ppt1(-/-) mice
Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL
Nature neuroscience22 Sep 2013
Ntbuha decreases lysosomal ceroid in human cells.
“mediated lysosomal ceroid depletion in cultured cells from INCL patients”
Cellsin cultured cells from INCL patients
Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL
Nature neuroscience22 Sep 2013

Latest

Nature Neuroscience22 Sep

Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL

Experiments in miceInterventions