Longevity-related metabolic pathway metabolites

1. Caloric restriction increases longevity-related metabolic pathway metabolites in humans.

   “metabolites associated with a longevity-related metabolic pathway increase with CR (p < 0.05)”

   Human trialoverweight/obesity8 weeks

   Gut microbiome remodeling and metabolomic profile improves in response to protein pacing with intermittent fasting versus continuous caloric restriction

   Nature communications·May 28, 2024

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