Long-chain ceramides

Biomarker

1 paper1 finding

  • Cells1

Upstream

1

GIMAP5

downin human cells1

1 study
  1. GIMAP5 decreases long-chain ceramides in human cells.

    “GIMAP5 restricts the pathological accumulation of long-chain ceramides (CERs), thereby regulating longevity”

    Cells

    GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway

    Nature immunology3 Jan 2024

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