Liver-to-body weight ratio

1. Retrorsine decreases liver-to-body weight ratio in mice.

   “By day 14 post-PH, the 70 mg/kg RTS/PH mice exhibited reduced liver-to-body weight ratios compared to control mice, indicating regeneration failureafter PH.”

   Animalsafter partial hepatectomyliver70 mg/kgday 14 post-PH

   Retrorsine impairs liver regeneration by inducing progenitor cell-senescence via ROS after partial hepatectomy

   Annals of medicine·3 Mar 2026

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