Liver cholesterol

Biomarker

2 papers1 finding

  • Animals2

Interventions

1

Aavrh.10-mnpc2-ha

downin mice1

1 study
  1. Aavrh.10-mnpc2-ha decreases liver cholesterol in mice.

    “significant reduction of liver cholesterol and sphingomyelin levels in treated Npc2-/- mice.”

    Animalsin Npc2-/- miceAAVrh.10-mNpc2-HAliver

    Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2

    Experimental neurology12 Apr 2018

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