2 papers2 findings
Polystyrene microplastics
upin worms1
Polystyrene microplastics increase lipofuscin accumulation in worms.
“Exposure to 100 μg/L PS-0 or PS-45 significantly shortened lifespan, impaired physiological behaviors, and increased lipofuscin accumulation”
Model organismsvirgin or 45-day photoaged100 μg/L
Environmental science & technology30 Jan 2026
Sulforaphane
downin worms1
Sulforaphane decreases lipofuscin accumulation in worms.
“Sulforaphane increased the lifespan and promoted a health-related phenotype by increasing mobility, appetite and food intake and reducing lipofuscin accumulation.”
Model organisms
Sulforaphane promotes C. elegans longevity and healthspan via DAF-16/DAF-2 insulin/IGF-1 signaling
Aging20 Jan 2021
The treatment relies on SKN-1 activation to increase collagen synthesis and enhance healthspan markers in Caenorhabditis elegans.The treatment relies on SKN-1 activation to increase collagen synthesis and enhance healthspan markers in Caenorhabditis elegans.