Lean mass

Biomarker3 papers3 findings

  • Humans3

Associations

3

FRAX

downin humans1

1 study
  1. Lean mass is associated with FRAX in humans.

    Humansfemalesn = 58

    Bone Health and Body Composition of Postmenopausal Exercisers and Sedentary Controls · International journal of sports medicine · 21 Aug 2026

FRAX →

Bone mineral density

upin humans1

1 study
  1. Lean mass is associated with bone mineral density in humans.

    Humansindependent of groupbonefemalesn = 58

    Bone Health and Body Composition of Postmenopausal Exercisers and Sedentary Controls · International journal of sports medicine · 21 Aug 2026

Bone mineral density →

Osteoporosis

downin humans1

1 study
  1. Lean mass predicts osteoporosis in humans (AUC 0.78±0.02).

    Humansin diabetic elderlyn = 469

    Association of body composition with bone mineral density and fracture in diabetic elderly: Results from AHAP study · Caspian journal of internal medicine · 10 Mar 2026

Osteoporosis →

Latest

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JCI InsightAnimals

Antibody reduced fat while preserving lean mass in mice

Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.

MedicineHumans

Genetically predicted TNF-beta protects against sarcopenia traits in humans

A Mendelian randomization analysis of 91 circulating inflammatory markers identified tumor necrosis factor-beta as causally linked to better muscle…A Mendelian randomization analysis of 91 circulating inflammatory markers identified tumor necrosis factor-beta as causally linked to better muscle mass, grip strength, and walking pace.