Knee extensor muscle strength

1. Knee extensor muscle strength is associated with cognitive decline in humans.

   “Notably, lower handgrip and knee extensor muscle strengths were associated with cognitive decline in participants ≥ 75-year-old.”

   Humansfemales

   Value of muscle strength in improving the predictive capability for cognitive decline in older women by established risk factors: A prospective cohort study in the Otassha Study

   Journal of Alzheimer's disease : JAD·Jun 30, 2025

1. Knee extensor muscle strength is linked with a lower risk of depressive symptoms in humans (OR 0.48 (95% CI 0.26, 0.91) for highest tertile).

   “the odds ratios (95% confidence interval) for depressive symptoms were 0.68 (0.39, 1.20) and 0.48 (0.26, 0.91) for the middle and highest tertiles of muscle strength”

   Humans2 yearsfemalesn = 768

   Knee Extensor Muscle Strength Associated with the Onset of Depression in Older Japanese Women: The Otassha Study

   Nutrients·Jul 9, 2024

More on Depressive symptoms

1. Knee extensor muscle strength is associated with frailty in humans after total hip arthroplasty (OR 0.980, 95% CI 0.964-0.996, p = 0.013).

   “knee extensor muscle strength (OR 0.980, 95% CI, 0.964-0.996; p = 0.013)”

   Humansafter total hip arthroplastyn = 518

   Prevalence of frailty and associated factors among community-dwelling older adults after total hip arthroplasty

   Hip international : the journal of clinical and experimental research on hip pathology and therapy·Sep 27, 2021