2 papers2 findings
Chronic obstructive pulmonary disease
mediatesin humans1
Klemera-Doubal biological age acceleration mediates chronic obstructive pulmonary disease in humans (14.3% mediated).
“KDM-BAAc mediated 14.3% (fully adjusted) of smoking's effect on COPD.”
Humanssmoking-COPD relationshipmean 3.4 yearsn = 1,269
BMC pulmonary medicine10 Jan 2026
Chronic obstructive pulmonary disease
upin humans1HR 1.07
Klemera-Doubal biological age acceleration raises the risk of chronic obstructive pulmonary disease in humans (HR = 1.07, 95% CI = 1.03-1.12).
“Each 1-year increase in KDM-BAAc elevated COPD risk by 7% [fully adjusted hazard ratio (HR) = 1.07, 95% CI = 1.03-1.12].”
Humansmean 3.4 yearsn = 1,269
BMC pulmonary medicine10 Jan 2026
The highest arterial stiffness tertile had higher risks of sarcopenia (HR 1.56) and probable sarcopenia (HR 1.38) compared with the lowest tertile.The highest arterial stiffness tertile had higher risks of sarcopenia (HR 1.56) and probable sarcopenia (HR 1.38) compared with the lowest tertile.