isoDGR

1 paper1 finding

Animals1

Effects

1

Blood-brain barrier breakdown

upin mice1

1 study

isoDGR induces blood-brain barrier breakdown in mice.
“age-associated accumulation of isoDGR in the brain cortex induces endothelial cytoskeletal collapse and tight junction disorganization, leading to BBB breakdown.”
Animalsbrain cortex
IsoDGR-Induced Endothelial Cytoskeletal Disruption Drives Age-Related Blood-Brain Barrier Breakdown
bioRxiv (Cold Spring Harbor Laboratory)14 Jul 2025Preprint

Latest

bioRxiv14 Jul

IsoDGR-Induced Endothelial Cytoskeletal Disruption Drives Age-Related Blood-Brain Barrier Breakdown

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