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Isocitrate lyase

Biomarker

1 paper studies it2 findings

MeSH

  • Cells1

Interventions

2

Rapamycin

no changein yeast cells1

1 study

  1. Rapamycin has no effect on isocitrate lyase in yeast cells.

    “Interestingly, rapamycin, a compound known for extending lifespan, does not increase the activity of the glyoxylate cycle enzyme.”

    Cells

    The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction-Mediated Extension of Lifespan in Budding Yeast

    Advanced biology

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Caloric restriction

upin yeast cells1

1 study

  1. Caloric restriction increases isocitrate lyase in yeast cells.

    “This analysis revealed an increase in isocitrate lyase activity, a key enzyme of the glyoxylate cycle, under CR”

    Cells

    The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction-Mediated Extension of Lifespan in Budding Yeast

    Advanced biology

More on Caloric restriction

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