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MLS1

Gene

1 paper studies it1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Cells1

Effects

1

Chronological lifespan extension

is required forin yeast cells1

1 study

  1. MLS1 is required for chronological lifespan extension in yeast cells.

    “not observed in mutants of the glyoxylate cycle, particularly those lacking genes for critical enzymes like isocitrate lyase 1 (icl1Δ) and malate synthase 1 (mls1Δ).”

    CellsRequired for caloric restriction-mediated extension; shown by MLS1 deletion

    The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction-Mediated Extension of Lifespan in Budding Yeast

    Advanced biologyMay 8, 2024

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