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ICL1

Gene

1 paper studies it1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Cells1

Effects

1

Chronological lifespan extension

is required forin yeast cells1

1 study

  1. ICL1 is required for chronological lifespan extension in yeast cells.

    “this beneficial effect of CR is not observed in mutants of the glyoxylate cycle, particularly those lacking genes for critical enzymes like isocitrate lyase 1 (icl1Δ)”

    CellsRequired for caloric restriction-mediated extension; shown by ICL1 deletion

    The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction-Mediated Extension of Lifespan in Budding Yeast

    Advanced biologyMay 8, 2024

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