Intracellular miR-195 and miR-188

1. Engineered mesenchymal stem cell-derived exosomes decrease intracellular miR-195 and miR-188 in cells.

   “Quantitative RT-PCR analysis confirmed that sponge-loaded exosomes significantly reduced intracellular levels of miR-195 and miR-188, demonstrating effective functional sequestration.”

   Cellsreplicative senescencedual miR-195/miR-188 sponge-loaded exosomesadipose-derived mesenchymal stem cell

   Synergistic reversal of mesenchymal stem cell senescence by engineered exosomal delivery of a dual miR-195/miR-188 sponge

   Experimental gerontology·8 Oct 2026

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