Research Square·Aug 16Combination antiretroviral therapy prevents SIV- induced aging in the hippocampus and neurodegeneration throughout the brainPreprint: experiments in monkeysInterventionsPaper
medRxiv·Aug 15Persistent obesity since childhood or adolescence accelerates biological aging in young adults from Chile’s oldest birth cohortPreprint: cohort study in peopleObesityPaper
American Journal of Reproductive Immunology·Jul 26Placental Senescence and the Two-Stage Model of PreeclampsiaReviewCellular senescencePaper
Biochimica et Biophysica Acta Molecular Basis of Disease·Jul 7Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cellsExperiments in miceProteostasisPaper
Epigenetics·May 31Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancerCohort study of 18 peopleGrimAgePaper
Acta Pharmacologica Sinica·May 25Mitochondrial calcium uniporter promotes kidney aging in mice through inducing mitochondrial calcium-mediated renal tubular cell senescenceExperiments in miceCellular senescencePaper
Journal of Alzheimer's Disease·Feb 2Traumatic Brain Injury Alters the Trajectory of Age-Related Mitochondrial ChangeExperiments in miceMitochondrionPaper
Acta Pharmacologica Sinica·Jan 11DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasisExperiments in miceMitochondrionPaper
IEEE Transactions on Neural Systems and Rehabilitation Engineering·Nov 1Age-Related Changes in Inter-Joint Interactions for Global and Local Kinematics While StandingCross-sectional study in peopleBones and jointsPaper
Journal of Affective Disorders·Oct 18Cognitive decline among older adults with depressive symptoms before and during the COVID-19 pandemicCohort study of 9,304 peoplePopulationsPaper
Journal of Neuroinflammation·Aug 1ATP-P2X₇R-mediated microglia senescence aggravates retinal ganglion cell injury in chronic ocular hypertensionCohort study of 48 peopleCellular senescencePaper
Aging Cell·Mar 21Mitochondrial function declines with age within individuals but is not linked to the pattern of growth or mortality risk in zebra finchExperiments in zebra finchesOxidative phosphorylationPaper
Cells·Mar 12Implications of Hypothalamic Neural Stem Cells on Aging and Obesity-Associated Cardiovascular DiseasesReviewMechanismsPaper
International Journal of Environmental Research and Public Health·Dec 24Epigenomic and Other Evidence for Cannabis-Induced Aging Contextualized in a Synthetic Epidemiologic Overview of Cannabinoid-Related Teratogenesis and Cannabinoid-Related CarcinogenesisReviewMechanismsPaper
Phytomedicine·Jul 7Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loopExperiments in miceBerberinePaper
Scientific Reports·May 26How social/environmental determinants and inflammation affect salivary telomere length among middle-older adults in the health and retirement studyCohort study in peoplePopulationsPaper
BMC Geriatrics·May 4Multiple events case-control study in a prospective cohort to identify systemic, cellular, and molecular biomarkers of obesity-induced accelerated aging in 30-years-olds: the ObAGE study protocolStudy protocolObesityPaper
Experimental Gerontology·Mar 23D-galactose-induced aging in rats - The effect of metformin on bioenergetics of brain, skeletal muscle and liverExperiments in ratsMetforminPaper
Clinical Medicine Insights Endocrinology and Diabetes·Nov 5Pleiotropic Benefits of DPP-4 Inhibitors Beyond Glycemic ControlReviewDPP-4 inhibitorsPaper
Biomolecules·Oct 24Bisphenol A Induces Accelerated Cell Aging in Murine EndotheliumExperiments in miceMechanismsPaper
Journal of Cellular and Molecular Medicine·Aug 21Cannabinoid receptor 2 plays a central role in renal tubular mitochondrial dysfunction and kidney ageingExperiments in miceMitochondrionPaper
Aging·Apr 21Characterization of murine mammary stem/progenitor cells in a D-galactose-induced aging modelExperiments in animalsMechanismsPaper
International Journal of Molecular Sciences·Apr 4Spectroscopic Signature of Red Blood Cells in a D-Galactose-Induced Accelerated Aging ModelExperiments in animalsMechanismsPaper
Cancers·Jan 28Cancer Treatment-Induced Accelerated Aging in Cancer Survivors: Biology and AssessmentReviewBiomarkersPaper
Biogerontology·Sep 27Spermidine, a caloric restriction mimetic, provides neuroprotection against normal and D-galactose-induced oxidative stress and apoptosis through activation of autophagy in male rats during agingExperiments in animalsInterventionsPaper
Neuro-oncology Practice·Aug 8Radiation-induced accelerated aging of the brain vasculature in young adult survivors of childhood brain tumorsStudy in peoplePopulationsPaper
Methods·Apr 13Hutchinson-Gilford progeria syndrome: Rejuvenating old drugs to fight accelerated ageingReviewInterventionsPaper
Aging Cell·Jul 19Wnt/β-catenin/RAS signaling mediates age-related renal fibrosis and is associated with mitochondrial dysfunctionExperiments in animalsMechanismsPaper
Biochemistry Biokhimiia·Jun 27Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles AgingExperiments in animalsMechanismsPaper