IL-1β expression

1 paper1 finding

Animals1

Upstream

1

ACSS2

upin cells1

1 study

ACSS2 increases IL-1β expression in cells.
“genetic and pharmacologic inhibition of ACSS2 both suppress H3K9cr-mediated IL-1β expression”
Cellsshown by genetic and pharmacologic inhibition of ACSS2
Inhibition of ACSS2-mediated histone crotonylation alleviates kidney fibrosis via IL-1β-dependent macrophage activation and tubular cell senescence
Nature communications13 Apr 2024

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