IL-17A and IL-17F production

Biomarker

1 paper2 findings

  • Cells1

Upstream

2

antioxidant signaling

is required forin human cells1

1 study
  1. antioxidant signaling is required for IL-17A and IL-17F production in human cells.

    “Everolimus's ability to alleviate the cytokines produced by Th17 subsets of T cells, such as IL-17A and IL-17F, was dependent on autophagy and antioxidant signaling pathways.”

    CellsRequired for everolimus-mediated reduction of cytokine productionTh17 cell0.01 μM

    Everolimus alleviates CD4⁺ T cell inflammation by regulating autophagy and cellular redox homeostasis

    GeroScience18 May 2024

Autophagy

is required forin human cells1

1 study
  1. Autophagy is required for IL-17A and IL-17F production in human cells.

    “Everolimus's ability to alleviate the cytokines produced by Th17 subsets of T cells, such as IL-17A and IL-17F, was dependent on autophagy and antioxidant signaling pathways.”

    CellsRequired for everolimus-mediated reduction of cytokine productionTh17 cell0.01 μM

    Everolimus alleviates CD4⁺ T cell inflammation by regulating autophagy and cellular redox homeostasis

    GeroScience18 May 2024

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