IL-17A and IL-17F production
1 paper2 findings
- Cells1
Upstream
2antioxidant signaling
is required forin human cells1
1 study
antioxidant signaling
is required forin human cells1
antioxidant signaling is required for IL-17A and IL-17F production in human cells.
“Everolimus's ability to alleviate the cytokines produced by Th17 subsets of T cells, such as IL-17A and IL-17F, was dependent on autophagy and antioxidant signaling pathways.”
CellsRequired for everolimus-mediated reduction of cytokine productionTh17 cell0.01 μM
GeroScience18 May 2024
Autophagy
is required forin human cells1
1 study
Autophagy
is required forin human cells1
Autophagy is required for IL-17A and IL-17F production in human cells.
“Everolimus's ability to alleviate the cytokines produced by Th17 subsets of T cells, such as IL-17A and IL-17F, was dependent on autophagy and antioxidant signaling pathways.”
CellsRequired for everolimus-mediated reduction of cytokine productionTh17 cell0.01 μM
GeroScience18 May 2024
Latest
GeroScience
Everolimus alleviates CD4⁺ T cell inflammation by regulating autophagy and cellular redox homeostasis
Experiments in human cellsBlood and immune system