What does the research say about IDH2 acetylation?

IDH2 acetylation

There are 2 papers on IDH2 acetylation in aging research: 1 observational study in people, 1 in animals. The newest story, Nov 13, 2026: “Raising an immune-cell protein eased liver injury in aged mice”.

Biomarker

2 papers study it1 finding

1 new paper in 30 daysSee all 2 papers on IDH2 acetylation

“In human liver grafts, low macrophage SIRT3 and high IDH2 acetylation pre-transplant predicted worse postoperative graft function.”

Targeting the macrophage sirtuin 3-isocitrate dehydrogenase 2 axis to mitigate ischemia-reperfusion injury in aged donor liversHepatobiliary & pancreatic diseases international : HBPD INT2026doi:10.1016/j.hbpd.2026.10.003

Humans1
Animals1

Associations

Postoperative graft function

downin humans1

1 study

IDH2 acetylation predicts postoperative graft function in humans (high pre-transplant IDH2 acetylation in liver transplant patients).
“In human liver grafts, low macrophage SIRT3 and high IDH2 acetylation pre-transplant predicted worse postoperative graft function.”
Humanshigh pre-transplant IDH2 acetylation in liver transplant patientsliver graft
Raising an immune-cell protein eased liver injury in aged mice
Hepatobiliary & pancreatic diseases international : HBPD INTOct 26, 2026

Latest

1 paper in 12 months

Hepatobiliary & Pancreatic Diseases InternationalNov 13

Raising an immune-cell protein eased liver injury in aged mice

In experiments, aged mice had less of the protein and more injury than young mice after liver blood supply was interrupted and restored.In experiments, aged mice had less of the protein and more injury than young mice after liver blood supply was interrupted and restored.

Mouse studyBlood and immune system

Paper

The Journals of Gerontology, Series AAug 16

Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis

Study in peopleLung