Hybrid extracellular vesicles
1 paper2 findings
- Animals1
Effects
2Mitochondrial membrane potential
downin human cells1
1 study
Mitochondrial membrane potential
downin human cells1
Hybrid extracellular vesicles decrease mitochondrial membrane potential in human cells.
“Mechanistically, hEVs decreased the mitochondrial membrane potential (ΔΨm) in an ADP/ATP translocase 1 (ADT1)-dependent manner”
Cellsin OA CSPCs
Innovation (Cambridge (Mass.))5 Jan 2026
Cellular senescence
upin humans1
1 study
Cellular senescence
upin humans1
Hybrid extracellular vesicles increase cellular senescence in humans.
“hEV administration increased chondrocyte damage, characterized by enhanced mitochondrial defects and cellular aging in OA models.”
Animalsin OA models
Innovation (Cambridge (Mass.))5 Jan 2026
Latest
1 in 12 monthsInnovation (Cambridge (Mass.))
Hybrid extracellular vesicles drive irreversible mitochondria damage and TCA metabolite deficiency-related chondrocyte senescence
Experiments in animalsCellular senescence