Horvath-SkinBlood epigenetic age acceleration

Any osteoarthritis progression is associated with Horvath-SkinBlood epigenetic age acceleration in humans (ΔEAA = 1.1 years).

“any progressor (pain+radiographic+dual) (ΔEAA = 1.1y, q = 0.02)”

HumansAny osteoarthritis progressor versus non-progressorsperipheral blood2-5 years

Borderline acceleration in blood epigenetic age of unclear biological importance in knee osteoarthritis progression: Specimens and data from the Osteoarthritis Initiative and Johnston County Osteoarthritis Project

Osteoarthritis and cartilage·4 Jun 2025

Dual osteoarthritis progression is associated with Horvath-SkinBlood epigenetic age acceleration in humans (ΔEAA = 1.2 years).

“dual progressors (pain+radiographic) (ΔEAA = 1.2y, q = 0.05)”

HumansDual pain and radiographic osteoarthritis progressors versus non-progressorsperipheral blood2-5 years

Borderline acceleration in blood epigenetic age of unclear biological importance in knee osteoarthritis progression: Specimens and data from the Osteoarthritis Initiative and Johnston County Osteoarthritis Project

Osteoarthritis and cartilage·4 Jun 2025

Radiographic osteoarthritis progression is associated with Horvath-SkinBlood epigenetic age acceleration in humans (ΔEAA = 1.5 years).

“Borderline epigenetic age acceleration was found among radiographic progressors using the SkinBlood calculator (difference in epigenetic age acceleration, ΔEAA=1.5 years, q = 0.02)”

HumansRadiographic osteoarthritis progressors versus non-progressorsperipheral blood2-5 years

Borderline acceleration in blood epigenetic age of unclear biological importance in knee osteoarthritis progression: Specimens and data from the Osteoarthritis Initiative and Johnston County Osteoarthritis Project

Osteoarthritis and cartilage·4 Jun 2025