Journal of Neurochemistry·May 12Anti-Aging Protein Klotho Attenuates Schizophrenia-Associated Cognitive and Synaptic Dysfunctions by Regulating GluN2B-NMDARs in the HippocampusExperiments in ratsSchizophreniaPaper
International Journal of Molecular Sciences·Apr 14Distinct and Overlapping Neuroprotective Efficacy of Silk Lutein and Sericin-Derived Oligopeptides from Yellow Silk Cocoons in Rodent Models of Aβ-Induced and Age-Related Cognitive DeclineExperiments in miceCognitive declinePaper
PNAS·Mar 3Functional recovery of the adult murine hippocampus after cryopreservation by vitrificationExperiments in animalsInterventionsPaper
Archives of Toxicology·Jan 17Chronic melamine cyanurate exposure impairs spatial learning and memory by altering autophagy-mediated synaptic plasticity and oxidative stress in the hippocampus of adolescent ratsExperiments in ratsAutophagyPaper
Journal of Inherited Metabolic Disease·Mar 1Spermidine Treatment Improves GRIN2B Loss-Of-Function, A Primary Disorder of Glutamatergic NeurotransmissionTrial in 2 peopleSpermidinePaper
Frontiers in Aging Neuroscience·Jun 4GluN2A or GluN2B subunits of the NMDA receptor contribute to changes in neuronal excitability and impairments in LTP in the hippocampus of aging mice but do not mediate detrimental effects of oligomeric Aβ (1-42)Experiments in miceMechanismsPaper
Psychopharmacology·Apr 17Coenzyme Q10 and exercise training reinstate middle cerebral artery occlusion-induced behavioral deficits and hippocampal long-term potentiation suppression in aging ratsExperiments in 50 ratsCoenzyme Q10Paper
bioRxiv·Oct 2A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse modelPreprint: experiments in animalsInterventionsPaper
Journal of Neuroinflammation·Feb 25Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruningExperiments in miceSynapsePaper
Brain, Behavior, and Immunity·Dec 23Intermittent systemic exposure to lipopolysaccharide-induced inflammation disrupts hippocampal long-term potentiation and impairs cognition in aging male miceExperiments in miceInflammationPaper
Journal of Functional Morphology and Kinesiology·Dec 24Hippocampal Adaptations to Continuous Aerobic Training: A Functional and Ultrastructural Evaluation in a Young Murine ModelExperiments in animalsInterventionsPaper
Neurochemistry International·Nov 8Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticityExperiments in ratsNLRP3Paper
ACS Chemical Neuroscience·Sep 11Epigallocatechin-3-Gallate Allosterically Activates Protein Kinase C-α and Improves the Cognition of Estrogen Deficiency MiceExperiments in miceEpigallocatechin gallatePaper
GeroScience·Aug 20Accumulation of C-terminal cleaved tau is distinctly associated with cognitive deficits, synaptic plasticity impairment, and neurodegeneration in aged miceExperiments in miceMechanismsPaper
Behavioral Neuroscience·Jun 8Hesperetin rescues emotional memory and synaptic plasticity deficit in aged ratsExperiments in ratsInterventionsPaper
Molecular Therapy Nucleic Acids·Mar 20AhR/miR-23a-3p/PKCα axis contributes to memory deficits in ovariectomized and normal aging female miceExperiments in miceMechanismsPaper
International Journal of Molecular Sciences·Jan 16Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's DiseaseExperiments in miceMechanismsPaper
The Journal of Neuroscience·Nov 4Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged MiceExperiments in miceTREM2Paper
Cellular and Molecular Life Sciences·May 30Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2Experiments in miceMechanismsPaper
Brain Research Bulletin·May 4Nicotinamide mononucleotide administration after sever hypoglycemia improves neuronal survival and cognitive function in ratsExperiments in ratsNicotinamide mononucleotidePaper
Aging·May 24Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive declineExperiments in miceInterventionsPaper
Zhongguo Zhong Yao Za Zhi·Apr 17Improved effects of saponins from Panax japonicus on decline of cognitive function in natural aging rats via NLRP3 inflammasome pathwayExperiments in 30 ratsInterventionsPaper
Neurobiology of Aging·Apr 1Systemic administration of a fibroblast growth factor receptor 1 agonist rescues the cognitive deficit in aged socially isolated ratsExperiments in ratsInterventionsPaper
The Journals of Gerontology, Series A·Jun 13Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive DeclineExperiments in miceSynaptic transmissionPaper
Neurobiology of Aging·Feb 9Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged miceExperiments in miceInterventionsPaper
Neuropharmacology·Nov 28Enhanced LTP in aged rats: Detrimental or compensatory?Experiments in ratsMechanismsPaper
Neurochemical Research·Nov 4Chronic Melatonin Administration Reduced Oxidative Damage and Cellular Senescence in the Hippocampus of a Mouse Model of Down SyndromeExperiments in miceMelatoninPaper
Neurobiology of Learning and Memory·Nov 28Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutaseExperiments in miceInterventionsPaper
The Journal of Neuroscience·Apr 12Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutaseExperiments in miceMechanismsPaper