High calculated 10-year hip fracture risk

Biomarker

1 paper2 findings

  • Humans1

Upstream

1

Removal of FRAX race/ethnicity calibration

upin humans1

1 study
  1. removal of FRAX race/ethnicity calibration increases high calculated 10-year hip fracture risk in humans (High-risk prevalence increased to 14.9% (Asian/PI), 10.9% (Hispanic), and 8.1% (Black)).

    “increasing to 14.9% (Asian/PI), 10.9% (Hispanic), and 8.1% (Black) without race/ethnicity calibration.”

    HumansAsian/Pacific Islander, Hispanic, and Black men with newly diagnosed prostate cancermales

    One in nine men with prostate cancer had high hip fracture risk

    Prostate cancer and prostatic diseases14 Oct 2026

Associations

1

Older age

upin humans1

1 study
  1. Older age is associated with high calculated 10-year hip fracture risk in humans (20.5% of men aged ≥65 years and 87.3% aged 80–89 years had 10yHIP ≥ 3%).

    “Age was a major risk factor; 20.5% of men aged ≥65 years, increasing to 87.3% of men aged 80-89 years had 10yHIP ≥ 3%.”

    Humansnewly diagnosed prostate cancer; high risk defined as 10yHIP ≥ 3%malesn = 25,413

    One in nine men with prostate cancer had high hip fracture risk

    Prostate cancer and prostatic diseases14 Oct 2026

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