AgingResearch.NewsJoin free

Havcr1 expression

Biomarker

2 papers study it2 findings

  • Animals2

Interventions

2

Fluvastatin

upin human cells1

1 study

  1. Fluvastatin increases Havcr1 expression in human cells.

    “combined exposure to fluvastatin and 25-HC increased kidney injury molecule-1 (KIM-1) expression in human induced pluripotent stem cell-derived kidney organoids.”

    Cellscombined with 25-hydroxycholesterolinduced pluripotent stem cell-derived kidney organoid

    Statins plus an immune-cell molecule killed kidney cells

    bioRxivPreprint

More on Fluvastatin

Nicotinamide mononucleotide

upin mice1

1 study

  1. Nicotinamide mononucleotide increases Havcr1 expression in mice.

    “Unexpectedly, in aged kidneys, NMN increased expression of genetic markers of inflammation (IL-1-beta; and Ccl2) and tubule injury (Kim-1).”

    Animalsaged micekidney300 mg/kg/day8 weeksmales

    Metabolite accumulation from oral NMN supplementation drives aging-specific kidney inflammation

    bioRxiv : the preprint server for biologyPreprint

More on Nicotinamide mononucleotide

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months
bioRxiv

Statins plus an immune-cell molecule killed kidney cells

In kidney cell experiments, atorvastatin and fluvastatin caused cell death when combined with 25-hydroxycholesterol, a cholesterol derivative made by activated immune…In kidney cell experiments, atorvastatin and fluvastatin caused cell death when combined with 25-hydroxycholesterol, a cholesterol derivative made by activated immune cells.

Preprint: cell studyKidney
Paper

Related