Circulating uremic toxins

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Nicotinamide mononucleotide

upin mice1

1 study

Nicotinamide mononucleotide increases circulating uremic toxins in mice.
“Metabolomics of endpoint sera showed that NMN-treated aged mice had higher circulating levels of uremic toxins than either aged controls or young NMN-treated mice.”
Animalscompared with aged controls or young NMN-treated miceserum300 mg/kg/day8 weeksmales
Metabolite accumulation from oral NMN supplementation drives aging-specific kidney inflammation
bioRxiv : the preprint server for biologyApr 22, 2024Preprint

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Preprint: experiments in miceNicotinamide mononucleotide