Cell Death Discovery
Loss of a regulatory protein worsened bone loss in mice
Experiments found that mice lacking SIRT5, a protein that modifies other proteins, had poorer bone formation and more severe bone loss than normal mice.Experiments found that mice lacking SIRT5, a protein that modifies other proteins, had poorer bone formation and more severe bone loss than normal mice.
Mouse studyBones and joints
Who was studiedMice lacking SIRT5, against wild-type controls
What changedBone loss was worse in mice lacking SIRT5 than in wild-type mice
The catchThe abstract omits sample sizes, making the reliability of the bone-loss result difficult to assess