iScience
Aging alters metabolism in some gut immune cells
Some immune cells in the small intestine showed metabolic changes with aging, while those in the colon were relatively resistant to fat buildup.Some immune cells in the small intestine showed metabolic changes with aging, while those in the colon were relatively resistant to fat buildup.
Experiments in animalsLipid and ceramide metabolism
Who was studiedGut muscularis macrophages, against colon macrophages
What changedFat buildup increased with aging in selected small-intestine macrophages, while colon macrophages were relatively resistant
The catchColon macrophages were relatively resistant, so the metabolic changes were not consistent across gut regions