GepiClock

Biomarker

1 paper1 finding

  • In silico1

Associations

1

Sensitivity to AKT and PI3Kα inhibitors

upin silico1

1 study
  1. GepiClock predicts sensitivity to AKT and PI3Kα inhibitors in silico.

    “Younger-predicted cell lines were more sensitive to mTOR, MEK1/2 and HSP90 inhibitors, whereas older lines showed increased sensitivity to AKT and PI3Kα inhibitors.”

    In silicocancer cell lines

    A Generalised Epigenetic Clock Reveals Therapeutic Vulnerabilities Linked to Ageing in Cancer Cells

    bioRxiv (Cold Spring Harbor Laboratory)26 Jun 2026Preprint

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