Papers on genomic stability

484 papers20 new in 30 days

Friday, January 1

The Journal of Frailty & AgingJan 1

The Relationship Between Vitamin D and Telomere/Telomerase: A Comprehensive Review

ReviewTelomerase and telomere maintenance

Paper

Thursday, December 10

Developmental DynamicsDec 10

DNA repair during regeneration in Ambystoma mexicanum

ReviewMechanisms

Paper

Saturday, December 5

Scientific ReportsDec 5

Deletion of the GAPDH gene contributes to genome stability in Saccharomyces cerevisiae

Experiments in cellsMechanisms

Paper

Friday, October 23

Aging CellOct 23

The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells

Experiments in mouse cellsInterventions

Paper

Saturday, September 26

Ageing Research ReviewsSep 26

Fight to the bitter end: DNA repair and aging

ReviewDNA repair

Paper

Sunday, September 13

International Journal of Molecular SciencesSep 13

A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice: Impact of Sex and Age

Experiments in miceDNA repair

Paper

Friday, September 11

Oxidative Medicine and Cellular LongevitySep 11

Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress

Experiments in human cellsAutophagy

Paper

Wednesday, September 2

The Journal of Cell BiologySep 2

Loss of CBX2 induces genome instability and senescence-associated chromosomal rearrangements

Experiments in mouse cellsCellular senescence

Paper

Tuesday, September 1

DNA RepairSep 1

NAD⁺-mediated regulation of mammalian base excision repair

ReviewDNA repair

Paper

Wednesday, August 26

Nature MetabolismAug 26

Glis1 facilitates induction of pluripotency via an epigenome-metabolome-epigenome signalling cascade

Experiments in cellsMechanisms

Paper

Sunday, August 9

Current NeuropharmacologyAug 9

SIRT1 Promotes Neuronal Fortification in Neurodegenerative Diseases through Attenuation of Pathological Hallmarks and Enhancement of Cellular Lifespan

ReviewSirtuin signaling

Paper

Friday, July 17

International Journal of Biological MacromoleculesJul 17

Potential roles of telomeres and telomerase in neurodegenerative diseases

ReviewTelomerase and telomere maintenance

Paper

Thursday, July 9

Molecular CellJul 9

Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging

Experiments in cellsMechanisms

Paper

Tuesday, June 23

Ageing Research ReviewsJun 23

Telomere transcription in ageing

ReviewTelomerase and telomere maintenance

Paper

Wednesday, June 17

Biomedical ReportsJun 17

Role of tumor suppressor molecules in genomic perturbations and damaged DNA repair involved in the pathogenesis of cancer and neurodegeneration (Review)

ReviewDNA repair

Paper

Saturday, June 13

OncogeneJun 13

The use of non-traditional models in the study of cancer resistance-the case of the naked mole rat

ReviewMechanisms

Paper

Thursday, June 11

The Journal of Biological ChemistryJun 11

Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators

ReviewSirtuin signaling

Paper

Monday, June 8

PNASJun 8

Elimination of rNMPs from mitochondrial DNA has no effect on its stability

Experiments in miceMitochondrion

Paper

Thursday, April 30

Frontiers in GeneticsApr 30

Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length

Genetic association study of 1,303 peopleTelomerase and telomere maintenance

Paper

Saturday, April 25

FEBS Open BioApr 25

Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition

Experiments in cellsMechanisms

Paper

Friday, April 10

Tissue Engineering Part C, MethodsApr 10

Dispersible and Dissolvable Porous Microcarrier Tablets Enable Efficient Large-Scale Human Mesenchymal Stem Cell Expansion

Experiments in cellsInterventions

Paper

Tuesday, March 10

EMBO ReportsMar 10

LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis

Experiments in cellsFOXO signaling

Paper

Saturday, March 7

Nature CommunicationsMar 7

Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina

Experiments in animalsInterventions

Paper

Sunday, February 23

Molecular NeurodegenerationFeb 23

Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

Experiments in miceMechanisms

Paper

Wednesday, January 15

MitochondrionJan 15

Relative telomere length and mitochondrial DNA copy number variation with age: Association with plasma folate and vitamin B12

Cross-sectional study of 428 peopleFolate

Paper

Friday, December 20

Aging CellDec 20

A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells

Experiments in yeastMechanisms

Paper

Wednesday, December 11

NutrientsDec 11

Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians

Cross-sectional study of 60 peopleBiomarkers

Paper

Tuesday, December 10

Oxidative Medicine and Cellular LongevityDec 10

Sex-Specific Negative Association between Iron Intake and Cellular Aging Markers: Mediation Models Involving TNFα

Cross-sectional study of 467 peoplePopulations

Paper

Sunday, December 1

Journal of Translational MedicineDec 1

The impact of cryopreservation on bone marrow-derived mesenchymal stem cells: a systematic review

ReviewInterventions

Paper

Tuesday, November 26

International Journal of Molecular SciencesNov 26

Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention

ReviewNicotinamide

Paper