Gene-body demethylation

Biomarker

1 paper1 finding

Animals1

Associations

muscle fiber-type switching

mixedin mice1

1 study

Gene-body demethylation is associated with muscle fiber-type switching in mice.
“These included coordinated gene-body demethylation and transcription that tracked with fiber-type switching in specific myonuclei.”
AnimalsFollowing voluntary wheel runningspecific myonuclei8 weeks
Exercise reshaped gene activity across tissues in mice
Cell15 Oct 2026

Latest

1 in 12 months

Cell1 h

Exercise reshaped gene activity across tissues in mice

An 8-week wheel-running experiment in mice examined 22 tissues and plasma, finding the largest gene-activity changes in skeletal muscle.An 8-week wheel-running experiment in mice examined 22 tissues and plasma, finding the largest gene-activity changes in skeletal muscle.

Experiments in miceInterventions

Paper

Gene-body demethylation

Associations

Latest

Exercise reshaped gene activity across tissues in mice

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