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National Institute of Mental HealthUS$1.3m
An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.
Processing more than 2,800 imaging sessions yielded 2,086 quality-checked sessions from 935 participants for research on aging and Alzheimer’s disease.Processing more than 2,800 imaging sessions yielded 2,086 quality-checked sessions from 935 participants for research on aging and Alzheimer’s disease.
Emergency department measurements of GrimAge and DunedinPACE biological aging markers tracked subsequent depressive symptoms and neural connectivity shifts in adults over…Emergency department measurements of GrimAge and DunedinPACE biological aging markers tracked subsequent depressive symptoms and neural connectivity shifts in adults over 35.
In 120 older adults, cerebrovascular reactivity and gray matter volume interacted in parietal and occipital lobes to influence executive function.In 120 older adults, cerebrovascular reactivity and gray matter volume interacted in parietal and occipital lobes to influence executive function.
Left parietal-putamen connectivity predicted better cognitive flexibility in young adults (r = 0.41) but worse performance in older adults (r = -0.33).Left parietal-putamen connectivity predicted better cognitive flexibility in young adults (r = 0.41) but worse performance in older adults (r = -0.33).