Skip to content
A
  • HomeHome
  • SearchSearch
  • AskAsk
  • SavedSaved
MechanismsHumans1,621 participants·Cohort study

Spatially convergent functional MRI signatures of diabetes and male sex identify genetic vulnerabilities to accelerated brain ageing

Graphical abstract from Brain Communications
Open the figure at full size
Graphical abstract · Chesebro et al.

Brain Communications

  • Insulin/IGF-1 signalling
  • Synaptic transmission
  • VEGF signalling
  • Type 2 diabetes
  • Humans

The paper

Chesebro AG, Rohm LR, Antal BB et al.

Brain Communications · 19 Sep 2026

doi.org/10.1093/braincomms/fcag347PubMed 42781427

More on Synaptic transmission

  • Microglial depletion triggers distinct molecular responses in male and female aged mouse brains

    bioRxiv · 2 Oct 2026

  • Dopamine clearance–cognition link varies by age and structure

    bioRxiv · 5 Oct 2026

  • APOE4 alters olfactory neurons across age and sex in mice

    bioRxiv · 4 Oct 2026

  • Restoring Tyr1R signaling aids motor function in flies

    bioRxiv · 5 Oct 2026

  • News
  • Trials
  • Topics
  • Evidence
  • Conferences
  • Stats
  • Updates
  • API
  • Plus

© 2026 AgingResearch.News

PrivacyTermsContact

    News

    See all →

    Direct AMPK activation modestly lengthens lifespan in short-lived species

    ResearchFight Aging!

    A protein complex with a bound molecule sits beside an unbound complex, with slightly more intact cells beneath the bound form and more fragments beneath the…

    Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

    ResearchNature Aging and 1 more

    Senescence-inhibiting isoform Δ133p53α slows premature aging in mice

    Researchnpj Aging

    Figure 1

    Trials

    See all →

    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered7 Oct 2026

    AI-Based Conversational Social Support for Older Adults With Heart Failure

    Chang Gung University of Science and Technology

    Trending

    Evidence →
    1. Intervention · 64 papersExercise
    2. Gene · 21 papersAPOE
    3. Disease · 122 papersCardiovascular disease
    4. Process · 117 papersInflammation
    5. Biomarker · 43 papersBody mass index
    6. Intervention · 42 papersGLP-1 receptor agonists

    Topics

    See all →
    • Mechanisms283
    • Interventions395
    • Biomarkers373
    • Populations545
    • AI & data141
    • Industry & policy24
    • Conferences
    • Stats
    • Updates
    • API
    • Plus
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News