FRIGHT clock
3 papers3 findings
- Animals3
Interventions
1Aerobic exercise
no changein mice1
1 study
Aerobic exercise
no changein mice1
Aerobic exercise has no effect on FRIGHT clock in mice.
“FRIGHT scores were unaffected by exercise”
Animals13 weeks
The journals of gerontology. Series A, Biological sciences and medical sciences7 Jan 2022
Associations
2Mortality
upin mice1
1 study
Mortality
upin mice1
FRIGHT clock is associated with mortality in mice.
“FRIGHT and frailty index, but not AFRAID, were associated with mortality.”
Animalsmales
Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy
The journals of gerontology. Series A, Biological sciences and medical sciences5 Jul 2022
Chronological age
upin silico1
1 study
Chronological age
upin silico1
FRIGHT clock predicts chronological age in silico.
“the FRIGHT (Frailty Inferred Geriatric Health Timeline) clock, a strong predictor of chronological age.”
In silico
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Nature communications15 Sep 2020
Latest
The Journals of Gerontology, Series A
Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy
Experiments in miceBiomarkers
Mechanisms of Ageing and Development
Serum testosterone concentrations are not associated with frailty in naturally ageing and testosterone-deficient older C57Bl/6 mice
Experiments in animalsMechanisms
The Journals of Gerontology, Series A
Aerobic Exercise Attenuates Frailty in Aging Male and Female C57Bl/6 Mice and Effects Systemic Cytokines Differentially by Sex
Experiments in miceAerobic exercise
Nature Communications
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Experiments in miceBiomarkers