AFRAID clock
3 papers2 findings
- Animals3
Interventions
1Aerobic exercise
downin mice1
1 study
Aerobic exercise
downin mice1
Aerobic exercise prevents AFRAID clock in mice.
“Exercise prevented the age-associated decline in AFRAID scores in older females such that exercised females had a longer life expectancy.”
Animals13 weeksfemales
The journals of gerontology. Series A, Biological sciences and medical sciences7 Jan 2022
Associations
1Lifespan
upin silico1
1 study
Lifespan
upin silico1
AFRAID clock predicts lifespan in silico.
“the AFRAID (Analysis of Frailty and Death) clock, which accurately predicts life expectancy and the efficacy of a lifespan-extending intervention up to a year in advance.”
In silico
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Nature communications15 Sep 2020
Latest
The Journals of Gerontology, Series A
Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy
Experiments in miceBiomarkers
Mechanisms of Ageing and Development
Serum testosterone concentrations are not associated with frailty in naturally ageing and testosterone-deficient older C57Bl/6 mice
Experiments in animalsMechanisms
The Journals of Gerontology, Series A
Aerobic Exercise Attenuates Frailty in Aging Male and Female C57Bl/6 Mice and Effects Systemic Cytokines Differentially by Sex
Experiments in miceAerobic exercise
Nature Communications
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Experiments in miceBiomarkers